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021-54845833/15800441009
中文名称： 兔抗ADAMTS5多克隆抗体
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Background: |
This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The encoded preproprotein is proteolytically processed to generate the mature enzyme. This enzyme contains two C-terminal TS motifs and functions as an aggrecanase that cleaves aggrecan, a major proteoglycan of cartilage, and may mediate cartilage destruction in osteoarthritis. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
ADAMTS5 |
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Immunogen: |
Synthetic peptide of human ADAMTS5 |
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Full name: |
ADAM metallopeptidase with thrombospondin type 1 motif 5 |
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Synonyms: |
ADMP-2; ADAM-TS5; ADAMTS-5; ADAMTS11; ADAM-TS 5; ADAMTS-11; ADAM-TS 11 |
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SwissProt: |
Q9UNA0 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human liver cancer |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
102 kDa |
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WB Positive control: |
Hela cell and Human placenta tissue lysates |
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WB Recommended dilution: |
500-2000 |
