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    ÖÐÎÄÃû³Æ£º VRK3 ¿¹Ô­£¨ÖØ×éµ°°×£©

    Ó¢ÎÄÃû³Æ£º VRK3 Antigen (Recombinant Protein)

    ±ð    Ãû£º vaccinia related kinase 3

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    Fusion protein corresponding to a region derived from 213-412 amino acids of human VRK3

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    Full name:

    vaccinia related kinase 3

    Swissprot:

    Q8IV63

    Gene Accession:

    BC023556

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    This gene encodes a member of the vaccinia-related kinase (VRK) family of serine/threonine protein kinases. In both human and mouse, this gene has substitutions at several residues within the ATP binding motifs that in other kinases have been shown to be required for catalysis. In vitro assays indicate the protein lacks phosphorylation activity. The protein, however, likely retains its substrate binding capability. This gene is widely expressed in human tissues and its protein localizes to the nucleus. Alternative splicing results in multiple transcripts encoding different isoforms.


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