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021-54845833/15800441009
中文名称 : 小鼠抗APEX1单克隆抗体
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Background: |
Apurinic/apyrimidinic (AP) sites occur frequently in DNA molecules by spontaneous hydrolysis, by DNA damaging agents or by DNA glycosylases that remove specific abnormal bases. AP sites are pre-mutagenic lesions that can prevent normal DNA replication so the cell contains systems to identify and repair such sites. Class II AP endonucleases cleave the phosphodiester backbone 5' to the AP site. This gene encodes the major AP endonuclease in human cells. Splice variants have been found for this gene; all encode the same protein. [provided by RefSeq, Jul 2008]. |
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Applications: |
WB, IHC |
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Name of antibody: |
APEX1 |
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Immunogen: |
Fusion protein of human APEX1 |
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Full name: |
APEX nuclease (multifunctional DNA repair enzyme) 1 (APEX1), transcript variant 1 |
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Synonyms: |
APE; APE1; APEN; APEX; APX; HAP1; REF1 |
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SwissProt: |
P27695 |
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IHC positive control: |
human colon tissue |
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IHC Recommend dilution: |
30-150 |
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WB Predicted band size: |
36 kDa |
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WB Positive control: |
HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, MCF-7 cell lysates |
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WB Recommended dilution: |
1000-5000 |
