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021-54845833/15800441009
中文名称 : 小鼠抗ANKMY2单克隆抗体
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Background: |
ANKMY2 (ankyrin repeat and MYND domain containing 2) is a 441 amino acid protein that contains three ANK repeats and one MYND-type zinc finger. Encoded by a gene that maps to human chromosome 7p21.1, ANKMY2 is conserved in chimpanzee, dog, cow, mouse, chicken, zebrafish, fruit fly, mosquito and Caenorhabditis elegans. Downregulation of ANKMY2, associated with frequent deletions of human chromosome 7p22.1, indicate that ANKMY2 may role a role in the pathogenesis of natural killer (NK)-cell malignancies. ANKMY2 is also upregulated by enforced expression of Hox11, which functions broadly to hinder hemopoiesis, diverts differentiation to an alternative fate and promotes pre-leukaemic states. ANKMY2 may also participate in zinc ion binding, cell adhesion, cellular morphogenesis, neurite outgrowth and human cortical functions. |
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Applications: |
WB, IHC |
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Name of antibody: |
ANKMY2 |
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Immunogen: |
Fusion protein of human ANKMY2 |
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Full name: |
ankyrin repeat and MYND domain containing 2 (ANKMY2) |
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Synonyms: |
ZMYND20 |
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SwissProt: |
Q8IV38 |
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IHC positive control: |
adenocarcinoma of human ovary tissue and adenocarcinoma of human breast tissue; human lymph node tissue and human kidney tissue |
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IHC Recommend dilution: |
30-150 |
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WB Predicted band size: |
49 kDa |
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WB Positive control: |
HepG2, Hela, SVT2, A549, COS7, Jurkat, MDCK, PC12, MCF-7 cell lysates |
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WB Recommended dilution: |
200-1000 |
