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中文名称：小鼠抗AFP单克隆抗体
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Background: |
This gene encodes alpha-fetoprotein, a major plasma protein produced by the yolk sac and the liver during fetal life. Alpha-fetoprotein expression in adults is often associated with hepatoma or teratoma. However, hereditary persistance of alpha-fetoprotein may also be found in individuals with no obvious pathology. The protein is thought to be the fetal counterpart of serum albumin, and the alpha-fetoprotein and albumin genes are present in tandem in the same transcriptional orientation on chromosome 4. Alpha-fetoprotein is found in monomeric as well as dimeric and trimeric forms, and binds copper, nickel, fatty acids and bilirubin. The level of alpha-fetoprotein in amniotic fluid is used to measure renal loss of protein to screen for spina bifida and anencephaly. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
AFP |
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Immunogen: |
Fusion protein of human AFP |
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Full name: |
alpha fetoprotein |
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Synonyms: |
AFPD; FETA; HPAFP |
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SwissProt: |
P02771 |
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IHC positive control: |
Human gastric |
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IHC Recommend dilution: |
40-200 |
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WB Predicted band size: |
69 kDa |
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WB Positive control: |
HepG2 whole cell lysate |
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WB Recommended dilution: |
1000-5000 |
