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中文名称：兔抗ZNF281多克隆抗体
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Background: |
Zinc-finger proteins contain DNA-binding domains and have a wide variety of functions, most of which encompass some form of transcriptional activation or repression. ZNF281, also known as GC-box-binding zinc finger protein 1, ZBP-99 or ZNP-99 (zinc finger DNA-binding protein 99), is a zinc finger protein that belongs to the Krüppel C2H2-type zinc finger protein family. It is expressed ubiquitously at low levels with predominant expression in kidney, liver, lymphocytes and placenta. ZNF281 localizes to the nucleus and contains four C2H2-type zinc fingers. ZNF281 plays a role in repressing the transcription of a variety of genes including Gastrin and ODC (ornithine decarboxylase). In particular, ZNF281 functions by binding to the G-rich box in the enhancer region of the gene. Upon DNA damage, ZNF281 may become phosphorylated by Atm or ATR. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
ZNF281 |
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Immunogen: |
Fusion protein of human ZNF281 |
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Full name: |
zinc finger protein 281 |
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Synonyms： |
ZBP-99; ZNP-99 |
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SwissProt: |
Q9Y2X9 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human thyroid cancer and human brain |
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IHC Recommend dilution: |
60-450 |
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WB Predicted band size: |
97 kDa |
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WB Positive control: |
A549 cell |
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WB Recommended dilution: |
500-2000 |
