购物车
帮助
021-54845833/15800441009
中文名称：小鼠抗ACLY(C-term)单克隆抗体
|
Background: |
ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. |
|
Applications: |
WB, IF, FC |
|
Name of antibody: |
ACLY(C-term) |
|
Immunogen: |
Fusion protein of human ACLY |
|
Full name: |
ATP citrate lyase |
|
Synonyms: |
ACL; ATPCL; CLATP |
|
SwissProt: |
P53396 |
|
WB Predicted band size: |
121 kDa |
|
WB Positive control: |
Hela, K562, COS7 and 3T3 cell lysates |
|
WB Recommended dilution: |
1000-5000 |
|
IF positive control: |
Hela cells |
|
IF Recommend dilution: |
50-150 |
|
FC Recommend dilution: |
50-100 |
