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中文名称：兔抗CEACAM1多克隆抗体
英文名称： Anti-CEACAM1 rabbit polyclonal antibody
别 名： BGP; BGP1; BGPI
相关类别： 一抗
储 存： 冷冻（-20℃）
宿 主： Rabbit
抗 原： CEACAM1
反应种属： Human
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
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Background: |
This gene encodes a member of the carcinoembryonic antigen (CEA) gene family, which belongs to the immunoglobulin superfamily. Two subgroups of the CEA family, the CEA cell adhesion molecules and the pregnancy-specific glycoproteins, are located within a 1.2 Mb cluster on the long arm of chromosome 19. Eleven pseudogenes of the CEA cell adhesion molecule subgroup are also found in the cluster. The encoded protein was originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it was found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. The encoded protein mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. Multiple cellular activities have been attributed to the encoded protein, including roles in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses. Multiple transcript variants encoding different isoforms have been reported, but the full-length nature of all variants has not been defined. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
CEACAM1 |
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Immunogen: |
Synthetic peptide of human CEACAM1 |
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Full name: |
carcinoembryonic antigen related cell adhesion molecule 1 |
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Synonyms: |
BGP; BGP1; BGPI |
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SwissProt: |
P13688 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human colorectal cancer and Human breast cancer |
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IHC Recommend dilution: |
10-50 |
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WB Predicted band size: |
58 kDa |
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WB Positive control: |
A549 cell lysate |
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WB Recommended dilution: |
500-2000 |
