Name: TPX2 抗原（重组蛋白）
Brand: 通蔚生物

中文名称： TPX2 抗原（重组蛋白）

英文名称： TPX2 Antigen (Recombinant Protein)

别名： TPX2, microtubule-associated; DIL2; p100; DIL-2; HCTP4; FLS353; HCA519; REPP86; C20orf1; C20orf2; GD:C20orf1

储存： 冷冻（-20℃）

相关类别：抗原

概述

Fusion protein corresponding to C terminal 200 amino acids of human TPX2

技术规格

Full name:	TPX2, microtubule-associated
Synonyms:	DIL2; p100; DIL-2; HCTP4; FLS353; HCA519; REPP86; C20orf1; C20orf2; GD:C20orf1
Swissprot:	Q9ULW0
Gene Accession:	BC004136
Purity:	>85%, as determined by Coomassie blue stained SDS-PAGE
Expression system:	Escherichia coli
Tags:	His tag C-Terminus, GST tag N-Terminus
Background:	TPX2 (targeting protein for Xklp2) is a microtubule-associated protein involved in targeting the motor protein Xklp2 to microtubules. Ran-GTP activates TPX2 for the chromatin-induced microbutule assembly during M phase. Aurora-A kinase associates with TPX2 at the spindle apparatus and may regulate TPX2 via phosphorylation during the spindle assembly. TPX2 appears to play a structural role in spindle formation. TPX2 activates Eg2 in a microtubule-dependent manner by stimulating the phosphorylation and kinase activity of Eg2.

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