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ÖÐÎÄÃû³Æ£ºÍÿ¹ZKSCAN3¶à¿Ë¡¿¹Ìå

Ó¢ÎÄÃû³Æ£º Anti-ZKSCAN3 rabbit polyclonal antibody

±ð       Ãû£º ZF47; Zfp47; ZFP306; ZNF306; ZNF309; zfp-47; ZSCAN13; ZSCAN35; dJ874C20.1; dJ874C20.1.

Ïà¹ØÀà±ð£º Ò»¿¹

¿¹       Ô­£º ZKSCAN3

´¢       ´æ£º Àä¶³£¨-20¡æ£©

ËÞ       Ö÷£º Rabbit

·´Ó¦ÖÖÊô£º Human, Mouse

±ê  ¼Ç  Î Unconjugate

¿Ë¡ÀàÐÍ£º Unconjugat

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Background:

Transcriptional factor that binds to the consensus sequence 5'-[GT][AG][AGT]GGGG-3' and acts as a repressor of autophagy. Specifically represses expression of genes involved in autophagy and lysosome biogenesis/function such as MAP1LC3B, ULK1 or WIPI2. Associates with chromatin at the ITGB4 and VEGF promoters. Also acts as a transcription activator and promotes cancer cell progression and/or migation in various tumors and myelomas.

Applications:

ELISA, IHC

Name of antibody:

ZKSCAN3

Immunogen:

Fusion protein of human ZKSCAN3

Full name:

zinc finger with KRAB and SCAN domains 3

Synonyms£º

ZF47; Zfp47; ZFP306; ZNF306; ZNF309; zfp-47; ZSCAN13; ZSCAN35; dJ874C20.1; dJ874C20.1.

SwissProt:

Q9BRR0

ELISA Recommended dilution:

5000-10000

IHC positive control:

Human gastric cancer

IHC Recommend dilution:

25-100



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