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中文名称：兔抗ZAK多克隆抗体
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Background: |
This gene is a member of the MAPKKK family of signal transduction molecules and encodes a protein with an N-terminal kinase catalytic domain, followed by a leucine zipper motif and a sterile-alpha motif (SAM). This magnesium-binding protein forms homodimers and is located in the cytoplasm. The protein mediates gamma radiation signaling leading to cell cycle arrest and activity of this protein plays a role in cell cycle checkpoint regulation in cells. The protein also has pro-apoptotic activity. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. |
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Applications: |
WB, IF |
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Name of antibody: |
ZAK |
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Immunogen: |
Synthesized peptide derived from C-terminal of human MLTK. |
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Full name: |
sterile alpha motif and leucine zipper containing kinase AZK |
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Synonyms： |
pk; AZK; MLT; MRK; MLK7; MLTK; mlklak |
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SwissProt: |
Q9NYL2 |
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WB Predicted band size: |
91 kDa |
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WB Positive control: |
Hela cells lysate |
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WB Recommended dilution: |
500-3000 |
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IF positive control: |
HepG2 cells |
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IF Recommend dilution: |
100-500 |
