购物车
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021-54845833/15800441009
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Background: |
The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed. |
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Applications: |
WB, IHC |
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Name of antibody: |
PRKAA1 |
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Immunogen: |
Fusion protein of human PRKAA1 |
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Full name: |
Protein kinase, AMP-activated, alpha 1 catalytic subunit |
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Synonyms: |
AMPK; AMPKa1 |
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SwissProt: |
Q13131 |
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IHC positive control: |
Human esophagus cancer and Human gastric cancer |
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IHC Recommend dilution: |
100-500 |
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WB Predicted band size: |
64 kDa |
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WB Positive control: |
Jurkat, 231 and NIH/3T3 cell lysates |
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WB Recommended dilution: |
500-2000 |
