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中文名称：兔抗CCR10多克隆抗体
英文名称： Anti-CCR10 rabbit polyclonal antibody
别 名： GPR2
抗 原： CCR10
储 存： 冷冻（-20℃）
宿 主： Rabbit
反应种属： Human, Mouse
相关类别： 一抗
标 记 物： Unconjugate
技术规格
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Background: |
Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues; the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27; MIM 604833); CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]). |
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Applications: |
ELISA, IHC |
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Name of antibody: |
CCR10 |
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Immunogen: |
Synthetic peptide of human CCR10 |
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Full name: |
chemokine (C-C motif) receptor 10 |
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Synonyms： |
GPR2 |
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SwissProt: |
P46092 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human prostate cancer and Human ovarian cancer |
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IHC Recommend dilution: |
20-100 |
