ÖÐÎÄÃû³Æ£ºÍÿ¹CCL5¶à¿Ë¡¿¹Ìå
Ó¢ÎÄÃû³Æ£º Anti-CCL5 rabbit polyclonal antibody
±ð Ãû£º C-C motif chemokine ligand 5 SISd; eoCP; SCYA5; RANTES; TCP228; D17S136E; SIS-delta
´¢ ´æ£º Àä¶³£¨-20¡æ£©
¿¹ Ô£º CCL5
ËÞ Ö÷£º Rabbit
Ïà¹ØÀà±ð£º Ò»¿¹
·´Ó¦ÖÖÊô£º Human, Mouse, Rat
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
¼¼Êõ¹æ¸ñ
|
Background: |
This gene is one of several chemokine genes clustered on the q-arm of chromosome 17. Chemokines form a superfamily of secreted proteins involved in immunoregulatory and inflammatory processes. The superfamily is divided into four subfamilies based on the arrangement of the N-terminal cysteine residues of the mature peptide. This chemokine, a member of the CC subfamily, functions as a chemoattractant for blood monocytes, memory T helper cells and eosinophils. It causes the release of histamine from basophils and activates eosinophils. This cytokine is one of the major HIV-suppressive factors produced by CD8+ cells. It functions as one of the natural ligands for the chemokine receptor chemokine (C-C motif) receptor 5 (CCR5), and it suppresses in vitro replication of the R5 strains of HIV-1, which use CCR5 as a coreceptor. Alternative splicing results in multiple transcript variants that encode different isoforms. |
|
Applications: |
ELISA, IHC |
|
Name of antibody: |
CCL5 |
|
Immunogen: |
Synthetic peptide of human CCL5 |
|
Full name: |
C-C motif chemokine ligand 5 |
|
Synonyms: |
SISd; eoCP; SCYA5; RANTES; TCP228; D17S136E; SIS-delta |
|
SwissProt: |
P13501 |
|
ELISA Recommended dilution: |
5000-10000 |
|
IHC positive control: |
Human liver cancer; |
|
IHC Recommend dilution: |
25-100 |
¹ºÎï³µ
°ïÖú
021-54845833/15800441009
