Ó¢ÎÄÃû³Æ£º Anti-CCL4 rabbit polyclonal antibody
±ð Ãû£º ACT2; G-26; HC21; LAG1; LAG-1; MIP1B; SCYA2; SCYA4; MIP1B1; AT744.1; MIP-1-beta
¿¹ Ô£º CCL4
´¢ ´æ£º Àä¶³£¨-20¡æ£©
ËÞ Ö÷£º Rabbit
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·´Ó¦ÖÖÊô£º Human, Rat
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
CCL4 |
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Immunogen: |
Fusion protein of human CCL4 |
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Full name: |
chemokine (C-C motif) ligand 4 |
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Synonyms£º |
ACT2; G-26; HC21; LAG1; LAG-1; MIP1B; SCYA2; SCYA4; MIP1B1; AT744.1; MIP-1-beta |
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SwissProt: |
P13236 |
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ELISA Recommended dilution: |
1000-5000 |
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IHC positive control: |
Human liver cancer and Human thyroid cancer |
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IHC Recommend dilution: |
50-200 |

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