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ÖÐÎÄÃû³Æ£ºÍÿ¹CCL4¶à¿Ë¡¿¹Ìå 

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Anti-CCL4 rabbit polyclonal antibody

±ð      Ãû£º ACT2; G-26; HC21; LAG1; LAG-1; MIP1B; SCYA2; SCYA4; MIP1B1; AT744.1; MIP-1-beta

¿¹      Ô­£º CCL4

´¢      ´æ£º Àä¶³£¨-20¡æ£©

ËÞ      Ö÷£º Rabbit

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·´Ó¦ÖÖÊô£º Human, Rat

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Unconjugate

¿Ë¡ÀàÐÍ£º rabbit polyclonal

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Background:

The protein encoded by this gene is a mitogen-inducible monokine and is one of the major HIV-suppressive factors produced by CD8+ T-cells. The encoded protein is secreted and has chemokinetic and inflammatory functions. Recombinant MIP-1-beta induces a dose-dependent inhibition of different strains of HIV-1, HIV-2, and simian immunodeficiency virus (SIV). The processed form MIP-1-beta(3-69) retains the abilities to induce down-modulation of surface expression of the chemokine receptor CCR5 and to inhibit the CCR5-mediated entry of HIV-1 in T-cells. MIP-1-beta(3-69) is also a ligand for CCR1 and CCR2 isoform B.

Applications:

ELISA, IHC

Name of antibody:

CCL4

Immunogen:

Fusion protein of human CCL4

Full name:

chemokine (C-C motif) ligand 4

Synonyms£º

ACT2; G-26; HC21; LAG1; LAG-1; MIP1B; SCYA2; SCYA4; MIP1B1; AT744.1; MIP-1-beta

SwissProt:

P13236

ELISA Recommended dilution:

1000-5000

IHC positive control:

Human liver cancer and Human thyroid cancer

IHC Recommend dilution:

50-200




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