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中文名称：兔抗CBL (phospho-Tyr700)多克隆抗体
别 名： CBL2; NSLL; C-CBL; RNF55; FRA11B
相关类别： 一抗
储 存： 冷冻（-20℃） 避光
宿 主： Rabbit
抗 原： CBL (phospho-Tyr700)
反应种属： Human, Mouse, Rat
标 记 物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
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Background: |
Participates in signal transduction in hematopoietic cells. Adapter protein that functions as a negative regulator of many signaling pathways that start from receptors at the cell surface. Acts as an E3 ubiquitin-protein ligase, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes, and then transfers it to substrates promoting their degradation by the proteasome. Recognizes activated receptor tyrosine kinases, including PDGFA, EGF and CSF1, and terminates signaling. |
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Applications: |
WB, IHC, IF |
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Name of antibody: |
CBL (phospho-Tyr700) |
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Immunogen: |
Synthetic peptide of human CBL (phospho-Tyr700) |
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Full name: |
Cbl proto-oncogene, E3 ubiquitin protein ligase (phospho-Tyr700) |
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Synonyms： |
CBL2; NSLL; C-CBL; RNF55; FRA11B |
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SwissProt: |
P22681 |
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IHC positive control: |
Human breast carcinoma |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
120 kDa |
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WB Positive control: |
HT29 cells treated with UV |
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WB Recommended dilution: |
500-1000 |
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IF Positive control: |
Hela cells |
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IF Recommended dilution |
100-200 |
