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    ÖÐÎÄÃû³Æ£ºÍÿ¹CARD8¶à¿Ë¡¿¹Ìå

    Ó¢ÎÄÃû³Æ£º
    Anti-CARD8 rabbit polyclonal antibody

    ±ð      Ãû£º CARD8; CARDINAL; DACAR; DKFZp779L0366; Dakar; FLJ18119; FLJ18121; KIAA0955; MGC57162; NDPP; NDPP1; TUCAN

    Ïà¹ØÀà±ð£º Ò»¿¹

    ¿¹      Ô­£º CARD8

    ´¢      ´æ£º Àä¶³£¨-20¡æ£© ±Ü¹â

    ËÞ      Ö÷£º Rabbit

    ·´Ó¦ÖÖÊô£º Human

    ±ê ¼Ç Î Unconjugate

    ¿Ë¡ÀàÐÍ£º rabbit polyclonal

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    Background:

    The protein encoded by this gene belongs to the caspase recruitment domain (CARD)-containing family of proteins, which are involved in pathways leading to activation of caspases or nuclear factor kappa-B (NFKB). This protein may be a component of the inflammasome, a protein complex that plays a role in the activation of proinflammatory caspases. It is thought that this protein acts as an adaptor molecule that negatively regulates NFKB activation, CASP1-dependent IL1B secretion, and apoptosis. Polymorphisms in this gene may be associated with a susceptibility to rheumatoid arthritis. Alternatively spliced transcript variants have been described for this gene, but their biological validity has not been determined.

    Applications:

    WB

    Name of antibody:

    CARD8

    Immunogen:

    Fusion protein of human CARD8

    Full name:

    Caspase recruitment domain-containing protein 8

    Synonyms£º

    CARD8; CARDINAL; DACAR; DKFZp779L0366; Dakar; FLJ18119; FLJ18121; KIAA0955; MGC57162; NDPP; NDPP1; TUCAN

    SwissProt:

    Q9Y2G2

    WB Predicted band size:

    49 kDa

    WB Positive control:

    K562 and Hela cells

    WB Recommended dilution:

    500-2000



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