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021-54845833/15800441009
中文名称： C12orf10 抗原（重组蛋白）
英文名称： C12orf10 Antigen (Recombinant Protein)
别 名： chromosome 12 open reading frame 10; MYG; MYG1; Gamm1; MST024; MSTP024
相关类别： 抗原
储 存： 冷冻（-20℃）
概 述
Fusion protein corresponding to a region derived from 156-376 amino acids of human C12orf10
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Full name: |
chromosome 12 open reading frame 10 |
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Synonyms: |
MYG; MYG1; Gamm1; MST024; MSTP024 |
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Swissprot: |
Q9HB07 |
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Gene Accession: |
BC028904 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
C12orf10, also known as MYG1, MYG1 is a 376 amino acid nucleo-mitochondrial protein belonging to the UPF0160 (MYG1) family. MYG1 is encoded by a gene that maps to human chromosome 12q13.13 and is ubiquitously expressed in simple as well as complex eukaryotes, with highest levels in testis. Considered to have a metal-dependent protein hydrolase (UPF0160) domain, MYG1 exhibits a mitochondrial targeting signal in the N-terminal region and a Pat7-type nuclear localization signal in the region between amino acids 33-39. Although MYG1 displays differential patterns and levels of expression during embryonic development, expression in normal adult tissues is stable, suggesting MYG1 involvement in early developmental processes and in adult stress/illness conditions. Elevation of MYG1 expression may be also associated with vitiligo susceptibility. |
