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    • Íÿ¹BMPR1B¶à¿Ë¡¿¹Ìå

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    ÖÐÎÄÃû³Æ£ºÍÿ¹BMPR1B¶à¿Ë¡¿¹Ìå

    Ó¢ÎÄÃû³Æ£º Anti-BMPR1B rabbit polyclonal antibody

    ±ð      Ãû£º ALK6; ALK-6; CDw293

    ¿¹      Ô­£º BMPR1B

    ´¢      ´æ£º Àä¶³£¨-20¡æ£©

    ËÞ      Ö÷£º Rabbit

    ·´Ó¦ÖÖÊô£º Human, Mouse

    Ïà¹ØÀà±ð£º Ò»¿¹

    ±ê ¼Ç Î Unconjugate

    ¿Ë¡ÀàÐÍ£º rabbit polyclonal

    ¼¼Êõ¹æ¸ñ

    Background:

    This gene encodes a member of the bone morphogenetic protein (BMP) receptor family of transmembrane serine/threonine kinases. The ligands of this receptor are BMPs, which are members of the TGF-beta superfamily. BMPs are involved in endochondral bone formation and embryogenesis. These proteins transduce their signals through the formation of heteromeric complexes of 2 different types of serine (threonine) kinase receptors: type I receptors of about 50-55 kD and type II receptors of about 70-80 kD. Type II receptors bind ligands in the absence of type I receptors, but they require their respective type I receptors for signaling, whereas type I receptors require their respective type II receptors for ligand binding.

    Applications:

    ELISA, IHC

    Name of antibody:

    BMPR1B

    Immunogen:

    Fusion protein of human BMPR1B

    Full name:

    bone morphogenetic protein receptor, type IB

    Synonyms£º

    ALK6; ALK-6; CDw293

    SwissProt:

    O00238

    ELISA Recommended dilution:

    2000-5000

    IHC positive control:

    Human thyroid cancer and human gastric cancer

    IHC Recommend dilution:

    25-100



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