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  • Íÿ¹BCR(Phospho-Tyr360)¶à¿Ë¡¿¹Ìå

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ÖÐÎÄÃû³Æ£ºÍÿ¹BCR(Phospho-Tyr360)¶à¿Ë¡¿¹Ìå

Ó¢ÎÄÃû³Æ£º Anti-BCR(Phospho-Tyr360) rabbit polyclonal antibody

±ð      Ãû£º ALL; CML; PHL; BCR1; D22S11; D22S662

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ËÞ      Ö÷£º Rabbit

¿¹      Ô­£º BCR(Phospho-Tyr360)

·´Ó¦ÖÖÊô£º Human Mouse Rat

±ê ¼Ç Î Unconjugate

¿Ë¡ÀàÐÍ£º rabbit polyclonal

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Background:

A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint.

Applications:

WB

Name of antibody:

BCR(Phospho-Tyr360)

Immunogen:

Peptide sequence around phosphorylation site of tyrosine 360 (T-T-Y(p)-R-M) derived from Human Bcr.

Full name:

breakpoint cluster region

Synonyms£º

ALL; CML; PHL; BCR1; D22S11; D22S662

SwissProt:

P11274

WB Predicted band size:

143 kDa

WB Positive control:

COS7 cells lysates

WB Recommended dilution:

500-1000



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