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Ó¢ÎÄÃû³Æ£º Anti-TNFRSF4 mouse monoclonal antibody
±ð Ãû£º TNF receptor superfamily member 4; OX40; ACT35; CD134; IMD16; TXGP1L
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ËÞ Ö÷£º Mouse
¿¹ Ô£º TNFRSF4
·´Ó¦ÖÖÊô£º Human
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º mouse monoclonal
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Background: |
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell proliferation and differentiation. |
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Applications: |
WB, FC |
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Name of antibody: |
TNFRSF4 |
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Immunogen: |
Fusion protein of human TNFRSF4 |
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Full name: |
TNF receptor superfamily member 4 |
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Synonyms: |
OX40; ACT35; CD134; IMD16; TXGP1L |
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SwissProt: |
P43489 |
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WB Predicted band size: |
29 KD |
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WB Positive control: |
PHA-PBMC cell lysate |
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WB Recommended dilution: |
200-1000 |
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FC Recommend dilution: |
50-100 |
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021-54845833/15800441009
