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Background: |
Participates in the translocation of transit peptide-containing proteins across the mitochondrial inner membrane. Also required for assembly of mitochondrial respiratory chain complex I and complex IV as component of some MITRAC complex, a cytochrome c oxidase (COX) assembly intermediate complex. TIM21 probably shuttles between the presequence translocase and respiratory-chain assembly intermediates in a process that promotes incorporation of early nuclear-encoded subunits into these complexes. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
TIMM21 |
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Immunogen: |
Fusion protein of human TIMM21 |
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Full name: |
translocase of inner mitochondrial membrane 21 |
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Synonyms: |
TIM21; HSPC154; C18orf55 |
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SwissProt: |
Q9BVV7 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human lung cancer; |
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IHC Recommend dilution: |
20-100 |
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WB Predicted band size: |
28 kDa |
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WB Positive control: |
SKOV3 cell lysate |
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WB Recommended dilution: |
200-1000 |
