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Background: |
This gene encodes a member of the vitamin B12-binding protein family. This family of proteins, alternatively referred to as R binders, is expressed in various tissues and secretions. This plasma protein binds cobalamin and mediates the transport of cobalamin into cells. This protein and other mammalian cobalamin-binding proteins, such as transcobalamin I and gastric intrisic factor, may have evolved by duplication of a common ancestral gene. Alternative splicing results in multiple transcript variants. |
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Applications: |
WB, IHC |
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Name of antibody: |
TCN2 |
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Immunogen: |
Fusion protein of human TCN2 |
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Full name: |
transcobalamin II |
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Synonyms： |
II; TC; TC2; TC-2; TCII; TC II; D22S676; D22S750 |
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SwissProt: |
P20062 |
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IHC positive control: |
Human liver cancer |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
48 kDa |
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WB Positive control: |
Human bladder carcinoma tissue |
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WB Recommended dilution: |
500-2000 |
