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Background: |
TAL-1 is a basic helix-loop-helix transcription. Regulates differentiation and survival during hemopoiesis. Implicated in the genesis of hemopoietic malignancies. It may play an important role in hemopoietic differentiation. Serves as a positive regulator of eryhtroid differentiation. Mutations are associated with T-cell leukemia and melanoma. Binds to the LIM domain containing protein Rhombotin-2. |
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Applications: |
WB |
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Name of antibody: |
TAL1(Phospho-Ser122) |
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Immunogen: |
Peptide sequence around phosphorylation site of Serine 122(Q-L-S(p)-P-P) derived from Human TAL-1. |
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Full name: |
T-cell acute lymphocytic leukemia 1 |
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Synonyms： |
SCL; TCL5; tal-1; bHLHa17 |
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SwissProt: |
P17542 |
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WB Predicted band size: |
34 kDa |
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WB Positive control: |
Jurkat cells lysates |
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WB Recommended dilution: |
500-1000 |
