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中文名称：兔抗APLF(Ab-116)多克隆抗体
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Background: |
Nuclease involved in single-strand and double-strand DNA break repair. Recruited to sites of DNA damage through interaction with poly(ADP-ribose), a polymeric post-translational modification synthesized transiently at sites of chromosomal damage to accelerate DNA strand break repair reactions. Displays apurinic-apyrimidinic (AP) endonuclease and 3'-5' exonuclease activities in vitro. Also able to introduce nicks at hydroxyuracil and other types of pyrimidine base damage. |
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Applications: |
WB, IHC |
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Name of antibody: |
APLF(Ab-116) |
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Immunogen: |
Synthesized non-phosphopeptide derived from human APLF around the phosphorylation site of serine 116 (R-N-S(p)-Q-V). |
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Full name: |
aprataxin and PNKP like factor |
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Synonyms： |
APFL; PALF; Xip1; ZCCHH1; C2orf13 |
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SwissProt: |
Q8IW19 |
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IHC positive control: |
Human brain tissue |
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IHC Recommend dilution: |
50-100 |
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WB Predicted band size: |
60 kDa |
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WB Positive control: |
HT-29 cells lysate |
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WB Recommended dilution: |
500-3000 |
