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021-54845833/15800441009
中文名称：兔抗APIP多克隆抗体
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Background: |
APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury.The protein highly expressed in skeletal muscle and heart and binds to the CARD of Apaf-1 in competition with caspase-9. Exogenous APIP inhibits cytochrome c-induced activation of caspase-3 and caspase-9, and suppresses cell death triggered by mitochondrial apoptotic stimuli through inhibiting the downstream activity of cytochrome c released from mitochondria. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
APIP |
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Immunogen: |
Fusion protein of human APIP |
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Full name: |
Probable methylthioribulose-1-phosphate dehydratase |
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Synonyms： |
APIP2, CGI29, CGI-29, MMRP19, dJ179L10.2 |
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SwissProt: |
Q96GX9 |
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ELISA Recommended dilution: |
500-5000 |
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IHC positive control: |
Human lung cancer |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
27 kDa |
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WB Positive control: |
Mouse heart tissue |
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WB Recommended dilution: |
200-1000 |
