ÖÐÎÄÃû³Æ£º Íÿ¹TRIB2¶à¿Ë¡¿¹Ìå
Ó¢ÎÄÃû³Æ£º Anti-TRIB2 rabbit polyclonal antibody
±ð Ãû£º C5FW; TRB2; GS3955
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ËÞ Ö÷£º Rabbit
¿¹ Ô£º TRIB2
·´Ó¦ÖÖÊô£º Human, Mouse
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
This gene encodes one of three members of the Tribbles family. The Tribbles members share a Trb domain, which is homologous to protein serine-threonine kinases, but lacks the active site lysine and probably lacks a catalytic function. The Tribbles proteins interact and modulate the activity of signal transduction pathways in a number of physiological and pathological processes. This Tribbles member induces apoptosis of cells mainly of the hematopoietic origin. It has been identified as a protein up-regulated by inflammatory stimuli in myeloid (THP-1) cells, and also as an oncogene that inactivates the transcription factor C/EBPalpha (CCAAT/enhancer-binding protein alpha) and causes acute myelogenous leukemia. Alternatively spliced transcript variants have been found for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
TRIB2 |
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Immunogen: |
Full length fusion protein |
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Full name: |
tribbles pseudokinase 2 |
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Synonyms£º |
C5FW; TRB2; GS3955 |
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SwissProt: |
Q92519 |
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ELISA Recommended dilution: |
2000-10000 |
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IHC positive control: |
Human gastric cancer |
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IHC Recommend dilution: |
30-150 |

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