购物车
帮助
021-54845833/15800441009
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Background: |
This gene encodes one of two sphingosine kinase isozymes that catalyze the phosphorylation of sphingosine into sphingosine 1-phosphate. Sphingosine 1-phosphate mediates many cellular processes including migration, proliferation and apoptosis, and also plays a role in several types of cancer by promoting angiogenesis and tumorigenesis. The encoded protein may play a role in breast cancer proliferation and chemoresistance. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
SPHK2 |
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Immunogen: |
Fusion protein of human SPHK2 |
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Full name: |
sphingosine kinase 2 |
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Synonyms： |
SK 2; SK-2; SPK 2; SPK-2 |
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SwissProt: |
Q9NRA0 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human thyroid cancer |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
69 kDa |
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WB Positive control: |
Mouse brain and liver tissue |
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WB Recommended dilution: |
200-1000 |
