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021-54845833/15800441009
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Background: |
Neuronal membrane glycoprotein M6-a is a protein that in humans is encoded by the GPM6A gene. Involved in neuronal differentiation, including differentiation and migration of neuronal stem cells. Plays a role in neuronal plasticity and is involved in neurite and filopodia outgrowth, filopodia motility and probably synapse formation. GPM6A-induced filopodia formation involves mitogen-activated protein kinase (MAPK) and Src signaling pathways. May be involved in neuronal NGF-dependent Ca2+ influx. May be involved in regulation of endocytosis and intracellular trafficking of G-protein-coupled receptors (GPCRs); enhances internalization and recycling of mu-type opioid receptor. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
GPM6A |
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Immunogen: |
Fusion protein of human GPM6A |
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Full name: |
glycoprotein M6A |
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Synonyms： |
M6A; GPM6 |
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SwissProt: |
P51674 |
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ELISA Recommended dilution: |
2000-10000 |
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IHC positive control: |
Human brain and human liver cancer |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
31 kDa |
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WB Positive control: |
Human fetal brain tissue |
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WB Recommended dilution: |
1000-5000 |
