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Ó¢ÎÄÃû³Æ£º Anti-SIGLEC5 rabbit polyclonal antibody
±ð Ãû£º CD170; OBBP2; CD33L2; OB-BP2; SIGLEC-5
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¿¹ Ô£º SIGLEC5
ËÞ Ö÷£º Rabbit
·´Ó¦ÖÖÊô£º Human
±ê¼ÇÎ Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
This gene encodes a member of the sialic acid-binding immunoglobulin-like lectin (Siglec) family. These cell surface lectins are characterized by structural motifs in the immunoglobulin (Ig)-like domains and sialic acid recognition sites in the first Ig V set domain. The encoded protein is a member of the CD33-related subset of Siglecs and inhibits the activation of several cell types including monocytes, macrophages and neutrophils. Binding of group B Streptococcus (GBS) to the encoded protein plays a role in GBS immune evasion. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
SIGLEC5 |
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Immunogen: |
Fusion protein of human SIGLEC5 |
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Full name: |
sialic acid binding Ig-like lectin 5 |
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Synonyms£º |
CD170; OBBP2; CD33L2; OB-BP2; SIGLEC-5 |
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SwissProt: |
O15389 |
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ELISA Recommended dilution: |
1000-2000 |
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IHC positive control: |
Human thyroid cancer and human brain |
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IHC Recommend dilution: |
25-100 |

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021-54845833/15800441009
