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ÖÐÎÄÃû³Æ£º Íÿ¹PCK1¶à¿Ë¡¿¹Ìå


Ó¢ÎÄÃû³Æ£º Anti-PCK1 rabbit polyclonal antibody


±ð      Ãû£º PEPCK1; PEPCKC; PEPCK-C


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´¢      ´æ£º Àä¶³£¨-20¡æ£©


ËÞ      Ö÷£º Rabbit


¿¹      Ô­£º PCK1


·´Ó¦ÖÖÊô£º Human, Mouse, Rat


±ê  ¼Ç  Î Unconjugate


¿Ë¡ÀàÐÍ£º rabbit polyclonal


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Background:

This gene is a main control point for the regulation of gluconeogenesis. The cytosolic enzyme encoded by this gene, along with GTP, catalyzes the formation of phosphoenolpyruvate from oxaloacetate, with the release of carbon dioxide and GDP. The expression of this gene can be regulated by insulin, glucocorticoids, glucagon, cAMP, and diet. Defects in this gene are a cause of cytosolic phosphoenolpyruvate carboxykinase deficiency. A mitochondrial isozyme of the encoded protein also has been characterized.

Applications:

ELISA, WB

Name of antibody:

PCK1

Immunogen:

Synthetic peptide of human PCK1

Full name:

phosphoenolpyruvate carboxykinase 1 (soluble)

Synonyms£º

PEPCK1; PEPCKC; PEPCK-C

SwissProt:

P35558

ELISA Recommended dilution:

2000-5000

WB Predicted band size:

69 kDa

WB Positive control:

Mouse liver and kidney tissue

WB Recommended dilution:

500-2000




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