ÖÐÎÄÃû³Æ : Íÿ¹PCDHA6¶à¿Ë¡¿¹Ìå
Ó¢ÎÄÃû³Æ : Anti-PCDHA6 rabbit polyclonal antibody
±ð Ãû : CNR2; CNRN2; CNRS2; CRNR2; PCDH-ALPHA6
¿¹ Ô : PCDHA6
´¢ ´æ : Àä¶³£¨-20¡æ£©
ËÞ Ö÷ : Rabbit
Ïà¹ØÀà±ð : Ò»¿¹
·´Ó¦ÖÖÊô : Human
±ê ¼Ç Îï : Unconjugate
¿Ë¡ÀàÐÍ : rabbit polyclonal
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Background: |
This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
PCDHA6 |
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Immunogen: |
Synthetic peptide of human PCDHA6 |
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Full name: |
protocadherin alpha 6 |
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Synonyms£º |
CNR2; CNRN2; CNRS2; CRNR2; PCDH-ALPHA6 |
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SwissProt: |
Q9UN73 |
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ELISA Recommended dilution: |
1000-2000 |
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IHC positive control: |
Human tonsil |
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IHC Recommend dilution: |
10-50 |

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021-54845833/15800441009
