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    µ±Ç°Î»ÖÃ: Ê×Ò³ > ¿ÆÑвúÆ· > ¿ÆÑп¹Ìå > Ò»¿¹ > Íÿ¹PAK1(Phospho-Ser199)¶à¿Ë¡¿¹Ìå

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    • Íÿ¹PAK1(Phospho-Ser199)¶à¿Ë¡¿¹Ìå

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    ÖÐÎÄÃû³Æ£º Íÿ¹PAK1(Phospho-Ser199) ¶à¿Ë¡¿¹Ìå


    Ó¢ÎÄÃû³Æ£º Anti-PAK1(Phospho-Ser199) rabbit polyclonal antibody


    ±ð      Ãû£º PAKalpha


    Ïà¹ØÀà±ð£º Ò»¿¹


    ´¢      ´æ£º Àä¶³£¨-20¡æ£© ±Ü¹â


    ËÞ      Ö÷£º Rabbit


    ¿¹      Ô­£ºPAK1(Phospho-Ser199)


    ·´Ó¦ÖÖÊô£º Human


    ±ê  ¼Ç  Î Unconjugate


    ¿Ë¡ÀàÐÍ£º rabbit polyclonal


    ¼¼Êõ¹æ¸ñ

    Background:

    The activated kinase acts on a variety of targets. Likely to be the GTPase effector that links the Rho-related GTPases to the JNK MAP kinase pathway. Activated by CDC42 and RAC1. Involved in dissolution of stress fibers and reorganization of focal complexes. Involved in regulation of microtubule biogenesis through phosphorylation of TBCB. Activity is inhibited in cells undergoing apoptosis, potentially due to binding of CDC2L1 and CDC2L2.

    Applications:

    WB, IHC

    Name of antibody:

    PAK1(Phospho-Ser199)

    Immunogen:

    Peptide sequence around phosphorylation site of Serine 199(T-K-S(p)-V-I) derived from Human PAK1.

    Full name:

    p21 protein (Cdc42/Rac)-activated kinase 1

    Synonyms£º

    PAKalpha

    SwissProt:

    Q13153

    IHC positive control:

    Human placenta tissue

    IHC Recommend dilution:

    50-100

    WB Predicted band size:

    61 kDa

    WB Positive control:

    LOVO cells lysates treated with starved

    WB Recommended dilution:

    500-1000







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