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    µ±Ç°Î»ÖÃ: Ê×Ò³ > ¿ÆÑвúÆ· > ¿ÆÑп¹Ìå > Ò»¿¹ > Íÿ¹OPTN¶à¿Ë¡¿¹Ìå

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    ÖÐÎÄÃû³Æ£º Íÿ¹OPTN¶à¿Ë¡¿¹Ìå


    Ó¢ÎÄÃû³Æ£º Anti-OPTN rabbit polyclonal antibody


    ±ð       Ãû£º NRP; FIP2; HIP7; HYPL; ALS12; GLC1E; TFIIIA-INTP


    Ïà¹ØÀà±ð£º Ò»¿¹


    ´¢       ´æ£º Àä¶³£¨-20¡æ£©


    ËÞ      Ö÷£º Rabbit


    ¿¹      Ô­£º OPTN


    ·´Ó¦ÖÖÊô£º Human, Mouse, Rat


    ±ê  ¼Ç  Î Unconjugate


    ¿Ë¡ÀàÐÍ£º rabbit polyclonal


    ¼¼Êõ¹æ¸ñ

    Background:

    This gene encodes the coiled-coil containing protein optineurin. Optineurin may play a role in normal-tension glaucoma and adult-onset primary open angle glaucoma. Optineurin interacts with adenovirus E3-14.7K protein and may utilize tumor necrosis factor-alpha or Fas-ligand pathways to mediate apoptosis, inflammation or vasoconstriction. Optineurin may also function in cellular morphogenesis and membrane trafficking, vesicle trafficking, and transcription activation through its interactions with the RAB8, huntingtin, and transcription factor IIIA proteins.

    Applications:

    ELISA, IHC

    Name of antibody:

    OPTN

    Immunogen:

    Fusion protein of human OPTN

    Full name:

    optineurin

    Synonyms£º

    NRP; FIP2; HIP7; HYPL; ALS12; GLC1E; TFIIIA-INTP

    SwissProt:

    Q96CV9

    ELISA Recommended dilution:

    1000-2000

    IHC positive control:

    Human thyroid cancer

    IHC Recommend dilution:

    25-100




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