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µ±Ç°Î»ÖÃ: Ê×Ò³ > ¿ÆÑвúÆ· > ¿ÆÑп¹Ìå > Ò»¿¹ > Íÿ¹NXF3¶à¿Ë¡¿¹Ìå

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  • Íÿ¹NXF3¶à¿Ë¡¿¹Ìå

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ÖÐÎÄÃû³Æ :   Íÿ¹NXF3¶à¿Ë¡¿¹Ìå



Ó¢ÎÄÃû³Æ :  Anti-NXF3 rabbit polyclonal antibody


¿¹       Ô­ :   NXF3


´¢       ´æ :   Àä¶³£¨-20¡æ£© ±Ü¹â


ËÞ      Ö÷ :   Rabbit


·´Ó¦ÖÖÊô :   Human


Ïà¹ØÀà±ð :   Ò»¿¹


±ê   ¼Ç  Îï :   Unconjugate


¿Ë¡ÀàÐÍ  :   Unconjugate


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Background:

This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus.

Applications:

WB

Name of antibody:

NXF3

Immunogen:

Synthesized peptide derived from internal of human NXF3.

Full name:

nuclear RNA export factor 3

Synonyms£º

0

SwissProt:

Q9H4D5

WB Predicted band size:

60 kDa

WB Positive control:

MCF-7 cells lysate

WB Recommended dilution:

500-3000




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