Ó¢ÎÄÃû³Æ : Anti-NXF3 rabbit polyclonal antibody
¿¹ Ô : NXF3
´¢ ´æ : Àä¶³£¨-20¡æ£© ±Ü¹â
ËÞ Ö÷ : Rabbit
·´Ó¦ÖÖÊô : Human
Ïà¹ØÀà±ð : Ò»¿¹
±ê ¼Ç Îï : Unconjugate
¿Ë¡ÀàÐÍ : Unconjugate
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Background: |
This gene is one member of a family of nuclear RNA export factor genes. Common domain features of this family are a noncanonical RNP-type RNA-binding domain (RBD), 4 leucine-rich repeats (LRRs), a nuclear transport factor 2 (NTF2)-like domain that allows heterodimerization with NTF2-related export protein-1 (NXT1), and a ubiquitin-associated domain that mediates interactions with nucleoporins. The LRRs and NTF2-like domains are required for export activity. Alternative splicing seems to be a common mechanism in this gene family. The encoded protein of this gene has shortened LRR and ubiquitin-associated domains and its RDB is unable to bind RNA. It is located in the nucleoplasm but is not associated with either the nuclear envelope or the nucleolus. |
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Applications: |
WB |
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Name of antibody: |
NXF3 |
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Immunogen: |
Synthesized peptide derived from internal of human NXF3. |
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Full name: |
nuclear RNA export factor 3 |
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Synonyms£º |
0 |
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SwissProt: |
Q9H4D5 |
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WB Predicted band size: |
60 kDa |
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WB Positive control: |
MCF-7 cells lysate |
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WB Recommended dilution: |
500-3000 |

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