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中文名称：兔抗SEMA4A多克隆抗体
英文名称： Anti-SEMA4A rabbit ployclonal antibody
别 名： RP35; SEMB; SEMAB; CORD10
相关类别： 一抗
储 存： 冷冻（-20℃）
宿 主： Rabbit
抗 原： SEMA4A
反应种属： Human
标记物： Unconjugate
克隆类型： rabbit polyclonal
技术规格
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Background: |
This gene encodes a member of the semaphorin family of soluble and transmembrane proteins. Semaphorins are involved in numerous functions, including axon guidance, morphogenesis, carcinogenesis, and immunomodulation. The encoded protein is a single-pass type I membrane protein containing an immunoglobulin-like C2-type domain, a PSI domain and a sema domain. It inhibits axonal extension by providing local signals to specify territories inaccessible for growing axons. It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo. Mutations in this gene are associated with retinal degenerative diseases including retinitis pigmentosa type 35 (RP35) and cone-rod dystrophy type 10 (CORD10). Multiple alternatively spliced transcript variants encoding different isoforms have been identified. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
SEMA4A |
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Immunogen: |
Fusion protein of human SEMA4A |
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Full name: |
sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4A |
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Synonyms： |
RP35; SEMB; SEMAB; CORD10 |
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SwissProt: |
Q9H3S1 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human prostate cancer |
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IHC Recommend dilution: |
25-100 |
