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Ó¢ÎÄÃû³Æ£º Anti-SELENOF rabbit polyclonal antibody
±ð Ãû£º selenoprotein F; SEP15
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ËÞ Ö÷£º Rabbit
¿¹ Ô£º SELENOF
·´Ó¦ÖÖÊô£º Human, Mouse, Rat
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
The protein encoded by this gene belongs to the SEP15/selenoprotein M family. The exact function of this protein is not known; however, it has been found to associate with UDP-glucose:glycoprotein glucosyltransferase (UGTR), an endoplasmic reticulum(ER)-resident protein, which is involved in the quality control of protein folding. The association with UGTR retains this protein in the ER, where it may play a role in protein folding. It has also been suggested to have a role in cancer etiology. This protein is a selenoprotein, containing the rare amino acid selenocysteine (Sec). Sec is encoded by the UGA codon, which normally signals translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, designated the Sec insertion sequence (SECIS) element, that is necessary for the recognition of UGA as a Sec codon, rather than as a stop signal. Alternatively spliced transcript variants have been found for this gene. |
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Applications: |
ELISA, WB |
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Name of antibody: |
SELENOF |
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Immunogen: |
Fusion protein of human SELENOF |
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Full name: |
selenoprotein F |
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Synonyms: |
SEP15 |
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SwissProt: |
O60613 |
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ELISA Recommended dilution: |
5000-10000 |
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WB Predicted band size: |
18 kDa |
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WB Positive control: |
Rat liver tissue lysate |
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WB Recommended dilution: |
1000-5000 |
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021-54845833/15800441009
