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    ÖÐÎÄÃû³Æ£º  Íÿ¹RHOV¶à¿Ë¡¿¹Ìå 

    Ó¢ÎÄÃû³Æ£º Anti-RHOV rabbit polyclonal antibody

    ±ð    Ãû£º CHP; ARHV; WRCH2

    Ïà¹ØÀà±ð£º Ò»¿¹

    ´¢    ´æ£º Àä¶³£¨-20¡æ£©

    ¿¹    Ô­£º RHOV

    ËÞ    Ö÷£º Rabbit

    ·´Ó¦ÖÖÊô£º Human, Mouse, Rat

    ±ê ¼Ç Î Unconjugate

    ¿Ë¡ÀàÐÍ£º rabbit polyclonal


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    Background:

    The Rho subfamily of Ras-related GTPases controls multiple aspects of cell function, including cytoskeletal rearrangement, nuclear signaling and cell growth. Rho V (ras homolog gene family, member V), also known as Rho GTPase-like protein ARHV, CHP or WRCH2 (Wnt-1 responsive Cdc42 homolog 2), is a 236 amino acid protein that controls the actin cytoskeleton through activation of the JNK pathway. A member of the Rho family and small GTPase superfamily, Rho V functions as a lipid anchor at the cytoplasmic side of the cell membrane and is expressed in placenta, pancreas and fetal brain. Rho V is implicated in cell transformation and is encoded by a gene located on human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes.

    Applications:

    ELISA, IHC

    Name of antibody:

    RHOV

    Immunogen:

    Full length fusion protein

    Full name:

    ras homolog family member V

    Synonyms£º

    CHP; ARHV; WRCH2

    SwissProt:

    Q96L33

    ELISA Recommended dilution:

    5000-10000

    IHC positive control:

    Human esophagus cancer and Human colorectal cancer

    IHC Recommend dilution:

    25-100



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