ÖÐÎÄÃû³Æ£º Íÿ¹RHOV¶à¿Ë¡¿¹Ìå
Ó¢ÎÄÃû³Æ£º Anti-RHOV rabbit polyclonal antibody
±ð Ãû£º CHP; ARHV; WRCH2
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¿¹ Ô£º RHOV
ËÞ Ö÷£º Rabbit
·´Ó¦ÖÖÊô£º Human, Mouse, Rat
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
The Rho subfamily of Ras-related GTPases controls multiple aspects of cell function, including cytoskeletal rearrangement, nuclear signaling and cell growth. Rho V (ras homolog gene family, member V), also known as Rho GTPase-like protein ARHV, CHP or WRCH2 (Wnt-1 responsive Cdc42 homolog 2), is a 236 amino acid protein that controls the actin cytoskeleton through activation of the JNK pathway. A member of the Rho family and small GTPase superfamily, Rho V functions as a lipid anchor at the cytoplasmic side of the cell membrane and is expressed in placenta, pancreas and fetal brain. Rho V is implicated in cell transformation and is encoded by a gene located on human chromosome 15, which houses over 700 genes and comprises nearly 3% of the human genome. Angelman syndrome, Prader-Willi syndrome, Tay-Sachs disease and Marfan syndrome are all associated with defects in chromosome 15-localized genes. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
RHOV |
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Immunogen: |
Full length fusion protein |
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Full name: |
ras homolog family member V |
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Synonyms£º |
CHP; ARHV; WRCH2 |
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SwissProt: |
Q96L33 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human esophagus cancer and Human colorectal cancer |
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IHC Recommend dilution: |
25-100 |
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021-54845833/15800441009