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021-54845833/15800441009
中文名称： 兔抗ERI1多克隆抗体
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Background: |
RNA exonuclease that binds to the 3'-end of histone mRNAs and degrades them, suggesting that it plays an essential role in histone mRNA decay after replication. A 2' and 3'-hydroxyl groups at the last nucleotide of the histone 3'-end is required for efficient degradation of RNA substrates. Also able to degrade the 3'-overhangs of short interfering RNAs (siRNAs) in vitro, suggesting a possible role as regulator of RNA interference (RNAi). Requires for binding the 5'-ACCCA-3' sequence present in stem-loop structure. Able to bind other mRNAs. Required for 5.8S rRNA 3'-end processing. Also binds to 5.8s ribosomal RNA. Binds with high affinity to the stem-loop structure of replication-dependent histone pre-mRNAs. |
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Applications: |
WB |
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Name of antibody: |
ERI1 |
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Immunogen: |
Synthesized peptide derived from internal of human ERI1. |
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Full name: |
exoribonuclease 1 |
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Synonyms： |
HEXO; THEX1; 3'HEXO |
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SwissProt: |
Q8IV48 |
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WB Predicted band size: |
40 kDa |
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WB Positive control: |
COLO205 cells lysate |
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WB Recommended dilution: |
500-3000 |
