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ÖÐÎÄÃû³Æ£ºÍÿ¹RAPGEF5¶à¿Ë¡¿¹Ìå  

Ó¢ÎÄÃû³Æ£º Anti-RAPGEF5 rabbit polyclonal antibody

±ð      Ãû£º GFR; REPAC; MR-GEF

¿¹      Ô­£º RAPGEF5

´¢      ´æ£º Àä¶³£¨-20¡æ£© ±Ü¹â

ËÞ      Ö÷£º Rabbit

Ïà¹ØÀà±ð£º Ò»¿¹

·´Ó¦ÖÖÊô£º Human Mouse

±ê¼ÇÎ Unconjugate

¿Ë¡ÀàÐÍ£º Unconjugate

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Background:

Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204])

Applications:

WB

Name of antibody:

RAPGEF5

Immunogen:

Synthesized peptide derived from internal of human RAPGEF5.

Full name:

Rap guanine nucleotide exchange factor (GEF) 5

Synonyms£º

GFR; REPAC; MR-GEF

SwissProt:

Q92565

WB Predicted band size:

68 kDa

WB Positive control:

RAW264.7 cells lysate

WB Recommended dilution:

500-3000



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