ÖÐÎÄÃû³Æ£ºÍÿ¹RAPGEF5¶à¿Ë¡¿¹Ìå
Ó¢ÎÄÃû³Æ£º Anti-RAPGEF5 rabbit polyclonal antibody
±ð Ãû£º GFR; REPAC; MR-GEF
¿¹ Ô£º RAPGEF5
´¢ ´æ£º Àä¶³£¨-20¡æ£© ±Ü¹â
ËÞ Ö÷£º Rabbit
Ïà¹ØÀà±ð£º Ò»¿¹
·´Ó¦ÖÖÊô£º Human Mouse
±ê¼ÇÎ Unconjugate
¿Ë¡ÀàÐÍ£º Unconjugate
¼¼Êõ¹æ¸ñ
|
Background: |
Members of the RAS (see HRAS; MIM 190020) subfamily of GTPases function in signal transduction as GTP/GDP-regulated switches that cycle between inactive GDP- and active GTP-bound states. Guanine nucleotide exchange factors (GEFs), such as RAPGEF5, serve as RAS activators by promoting acquisition of GTP to maintain the active GTP-bound state and are the key link between cell surface receptors and RAS activation (Rebhun et al., 2000 [PubMed 10934204]) |
|
Applications: |
WB |
|
Name of antibody: |
RAPGEF5 |
|
Immunogen: |
Synthesized peptide derived from internal of human RAPGEF5. |
|
Full name: |
Rap guanine nucleotide exchange factor (GEF) 5 |
|
Synonyms£º |
GFR; REPAC; MR-GEF |
|
SwissProt: |
Q92565 |
|
WB Predicted band size: |
68 kDa |
|
WB Positive control: |
RAW264.7 cells lysate |
|
WB Recommended dilution: |
500-3000 |

¹ºÎï³µ
°ïÖú
021-54845833/15800441009