ÖÐÎÄÃû³Æ£º Íÿ¹RAB38¶à¿Ë¡¿¹Ìå
Ó¢ÎÄÃû³Æ£º Anti-RAB38 rabbit polyclonal antibody
±ð Ãû£º RAB38, member RAS oncogene family; rrGTPbp; NY-MEL-1
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ËÞ Ö÷£º Rabbit
¿¹ Ô£º RAB38
·´Ó¦ÖÖÊô£º Human, Mouse
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
Background:
May be involved in melanosomal transport and docking. Involved in the proper sorting of TYRP1. Involved in peripheral melanosomal distribution of TYRP1 in melanocytes; the function, which probably is implicating vesicle-trafficking, includes cooperation with ANKRD27 and VAMP7 (By similarity). Plays a role in the maturation of phagosomes that engulf pathogens, such as S.aureus and M.tuberculosis (PubMed:21255211). Plays an important role in the control of melanin production and melanosome biogenesis (PubMed:23084991). In concert with RAB32, regulates the proper trafficking of melanogenic enzymes TYR, TYRP1 and DCT/TYRP2 to melanosomes in melanocytes (By similarity).
Applications:
ELISA, WB, IHC
Name of antibody:
RAB38
Immunogen:
Fusion protein of human RAB38
Full name:
RAB38, member RAS oncogene family
Synonyms:
rrGTPbp; NY-MEL-1
SwissProt:
P57729
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human liver cancer and Human prostate cancer
IHC Recommend dilution:
50-200
WB Predicted band size:
24 kDa
WB Positive control:
NIH/3T3 cell lysate
WB Recommended dilution:
500-2000
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