Ó¢ÎÄÃû³Æ£º Anti-PTPRG rabbit polyclonal antibody
±ð Ãû£º PTPG; HPTPG; RPTPG; R-PTP-GAMMA
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ËÞ Ö÷£º Rabbit
¿¹ Ô£º PTPRG
·´Ó¦ÖÖÊô£º Human, Mouse
±ê¼ÇÎ Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background:
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this PTP contains a carbonic anhydrase-like (CAH) domain, which is also found in the extracellular region of PTPRBETA/ZETA. This gene is located in a chromosomal region that is frequently deleted in renal cell carcinoma and lung carcinoma, thus is thought to be a candidate tumor suppressor gene.
Applications:
ELISA, IHC
Name of antibody:
PTPRG
Immunogen:
Synthetic peptide of human PTPRG
Full name:
protein tyrosine phosphatase receptor type G
Synonyms:
PTPG; HPTPG; RPTPG; R-PTP-GAMMA
SwissProt:
P23470
ELISA Recommended dilution:
5000-10000
IHC positive control:
Human colorectal cancer
IHC Recommend dilution:
50-200

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021-54845833/15800441009
