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021-54845833/15800441009
中文名称： 兔抗EIF4G1多克隆抗体
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Background: |
The protein encoded by this gene is a component of the multi-subunit protein complex EIF4F. This complex facilitates the recruitment of mRNA to the ribosome, which is a rate-limiting step during the initiation phase of protein synthesis. The recognition of the mRNA cap and the ATP-dependent unwinding of 5'-terminal secondary structure is catalyzed by factors in this complex. The subunit encoded by this gene is a large scaffolding protein that contains binding sites for other members of the EIF4F complex. A domain at its N-terminus can also interact with the poly(A)-binding protein, which may mediate the circularization of mRNA during translation. Alternative splicing results in multiple transcript variants, some of which are derived from alternative promoter usage. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
EIF4G1 |
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Immunogen: |
Synthetic peptide of human EIF4G1 |
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Full name: |
eukaryotic translation initiation factor 4 gamma, 1 |
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Synonyms： |
P220; EIF4F; EIF4G; EIF4GI; PARK18; EIF-4G1 |
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SwissProt: |
Q04637 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human thyroid cancer and Human gastric cancer |
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IHC Recommend dilution: |
25-100 |
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WB Predicted band size: |
175 kDa |
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WB Positive control: |
Lovo and 293T cells |
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WB Recommended dilution: |
500-2000 |
