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Background: |
This gene encodes a member of a family of kinases that phosphorylate the alpha subunit of eukaryotic translation initiation factor-2 (EIF2), resulting in the downregulaton of protein synthesis. The encoded protein responds to amino acid deprivation by binding uncharged transfer RNAs. It may also be activated by glucose deprivation and viral infection. Mutations in this gene have been found in individuals suffering from autosomal recessive pulmonary venoocclusive-disease-2. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
EIF2AK4 |
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Immunogen: |
Fusion protein of human EIF2AK4 |
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Full name: |
eukaryotic translation initiation factor 2 alpha kinase 4 |
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Synonyms： |
GCN2; PVOD2 |
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SwissProt: |
Q9P2K8 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human breast cancer and Human liver cancer |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
187 kDa |
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WB Positive control: |
293T cell |
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WB Recommended dilution: |
500-2000 |
