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    µ±Ç°Î»ÖÃ: Ê×Ò³ > ¿ÆÑвúÆ· > ¿ÆÑп¹Ìå > Ò»¿¹ > Íÿ¹GSKIP¶à¿Ë¡¿¹Ìå

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    • Íÿ¹GSKIP¶à¿Ë¡¿¹Ìå

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    ÖÐÎÄÃû³Æ: Íÿ¹GSKIP¶à¿Ë¡¿¹Ìå

    Ó¢ÎÄÃû³Æ: Anti-GSKIP rabbit polyclonal antibody

    ±ð   Ãû: GSK3B interacting protein; HSPC210; C14orf129

    ¿¹   Ô­: GSKIP

    ´¢   ´æ: Àä¶³£¨-20¡æ£©

    ËÞ   Ö÷: Rabbit

    ·´Ó¦ÖÖÊô: Human, Mouse, Rat

    Ïà¹ØÀà±ð: Ò»¿¹

    ±ê ¼Ç Îï: Unconjugate

    ¿Ë¡ÀàÐÍ: rabbit polyclonal

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    Background:

    This gene encodes a protein that is involved as a negative regulator of GSK3-beta in the Wnt signaling pathway. The encoded protein may play a role in the retinoic acid signaling pathway by regulating the functional interactions between GSK3-beta, beta-catenin and cyclin D1, and it regulates the beta-catenin/N-cadherin pool. The encoded protein contains a GSK3-beta interacting domain (GID) in its C-terminus, which is similar to the GID of Axin. The protein also contains an evolutionarily conserved RII-binding domain, which facilitates binding with protein kinase-A and GSK3-beta, enabling its role as an A-kinase anchoring protein. Alternatively spliced transcript variants have been observed for this gene.

    Applications:

    ELISA, IHC

    Name of antibody:

    GSKIP

    Immunogen:

    Fusion protein of human GSKIP

    Full name:

    GSK3B interacting protein

    Synonyms:

    HSPC210; C14orf129

    SwissProt:

    Q9P0R6

    ELISA Recommended dilution:

    5000-10000

    IHC positive control:

    Human cervical cancer

    IHC Recommend dilution:

    30-150






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