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021-54845833/15800441009
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Background: |
Dynamins represent one of the subfamilies of GTP-binding proteins. These proteins share considerable sequence similarity over the N-terminal portion of the molecule, which contains the GTPase domain. Dynamins are associated with microtubules. They have been implicated in cell processes such as endocytosis and cell motility, and in alterations of the membrane that accompany certain activities such as bone resorption by osteoclasts. Dynamins bind many proteins that bind actin and other cytoskeletal proteins. Dynamins can also self-assemble, a process that stimulates GTPase activity. Five alternatively spliced transcripts encoding different proteins have been described. |
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Applications: |
ELISA, WB, IHC |
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Name of antibody: |
DNM2 |
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Immunogen: |
Synthetic peptide of human DNM2 |
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Full name: |
dynamin 2 |
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Synonyms： |
DYN2; CMT2M; DYNII; LCCS5; CMTDI1; CMTDIB; DI-CMTB |
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SwissProt: |
P50570 |
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ELISA Recommended dilution: |
2000-5000 |
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IHC positive control: |
Human thyroid cancer and Human gastric cancer |
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IHC Recommend dilution: |
50-200 |
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WB Predicted band size: |
98 kDa |
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WB Positive control: |
Raji cells and human fetal liver tissue, NIH/3T3 cells and mouse brain tissue, hela cells |
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WB Recommended dilution: |
500-2000 |
