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021-54845833/15800441009
中文名称 : 小鼠抗CA12单克隆抗体
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Background: |
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. This gene product is a type I membrane protein that is highly expressed in normal tissues, such as kidney, colon and pancreas, and has been found to be overexpressed in 10% of clear cell renal carcinomas. Two transcript variants encoding different isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]. |
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Applications: |
WB, IHC |
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Name of antibody: |
CA12 |
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Immunogen: |
Fusion protein of human CA12 |
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Full name: |
carbonic anhydrase XII (CA12), transcript variant 1 |
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Synonyms: |
CAXII; HsT18816 |
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SwissProt: |
O43570 |
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IHC positive control: |
human pancreas tissue and human colon tissue; human kidney tissue and carcinoma of human kidney tissue |
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IHC Recommend dilution: |
30-150 |
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WB Predicted band size: |
39 kDa |
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WB Positive control: |
A549 cell lysate |
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WB Recommended dilution: |
500-2000 |
