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    Ó¢ÎÄÃû³Æ£º EIF2B3 Antigen (Recombinant Protein)

    ±ð      Ãû£º eukaryotic translation initiation factor 2B subunit gamma; EIF-2B; EIF2Bgamma

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    Fusion protein corresponding to a region derived from 202-401 amino acids of human EIF2B3


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    Full name:

    eukaryotic translation initiation factor 2B subunit gamma

    Synonyms:

    EIF-2B; EIF2Bgamma

    Swissprot:

    Q9NR50

    Gene Accession:

    BC018728

    Purity:

    >85%, as determined by Coomassie blue stained SDS-PAGE

    Expression system:

    Escherichia coli

    Tags:

    His tag C-Terminus, GST tag N-Terminus

    Background:

    The protein encoded by this gene is one of the subunits of initiation factor eIF2B, which catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. It has also been found to function as a cofactor of hepatitis C virus internal ribosome entry site-mediated translation. Mutations in this gene have been associated with leukodystrophy with vanishing white matter. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.


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