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中文名称：ADH5 抗原（重组蛋白）
英文名称： ADH5 Antigen (Recombinant Protein)
别 名： alcohol dehydrogenase 5 (class III), chi polypeptide; FDH; ADHX; ADH-3; FALDH; GSNOR; GSH-FDH; HEL-S-60p
储 存： 冷冻（-20℃）
相关类别： 抗原
概 述：
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Fusion protein corresponding to a region derived from 175-374 amino acids of human ADH5 |
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Full name: |
alcohol dehydrogenase 5 (class III), chi polypeptide |
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Synonyms: |
FDH; ADHX; ADH-3; FALDH; GSNOR; GSH-FDH; HEL-S-60p |
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Swissprot: |
P11766 |
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Gene Accession: |
BC014665 |
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Purity: |
>85%, as determined by Coomassie blue stained SDS-PAGE |
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Expression system: |
Escherichia coli |
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Tags: |
His tag C-Terminus, GST tag N-Terminus |
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Background: |
This gene encodes a member of the alcohol dehydrogenase family. Members of this family metabolize a wide variety of substrates, including ethanol, retinol, other aliphatic alcohols, hydroxysteroids, and lipid peroxidation products. The encoded protein forms a homodimer. It has virtually no activity for ethanol oxidation, but exhibits high activity for oxidation of long-chain primary alcohols and for oxidation of S-hydroxymethyl-glutathione, a spontaneous adduct between formaldehyde and glutathione. This enzyme is an important component of cellular metabolism for the elimination of formaldehyde, a potent irritant and sensitizing agent that causes lacrymation, rhinitis, pharyngitis, and contact dermatitis. The human genome contains several non-transcribed pseudogenes related to this gene. |
