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Ó¢ÎÄÃû³Æ£º Anti-MED23 rabbit polyclonal antibody
±ð Ãû£º mediator complex subunit 23 SUR2; CRSP3; MRT18; SUR-2; ARC130; CRSP130; CRSP133; DRIP130
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´¢ ´æ£º Àä¶³£¨-20¡æ£©
¿¹ Ô£º MED23
ËÞ Ö÷£º Rabbit
·´Ó¦ÖÖÊô£º Human, Mouse, Rat
±ê ¼Ç Î Unconjugate
¿Ë¡ÀàÐÍ£º rabbit polyclonal
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Background: |
The activation of gene transcription is a multistep process that is triggered by factors that recognize transcriptional enhancer sites in DNA. These factors work with co-activators to direct transcriptional initiation by the RNA polymerase II apparatus. The protein encoded by this gene is a subunit of the CRSP (cofactor required for SP1 activation) complex, which, along with TFIID, is required for efficient activation by SP1. This protein is also a component of other multisubunit complexes e.g. thyroid hormone receptor-(TR-) associated proteins which interact with TR and facilitate TR function on DNA templates in conjunction with initiation factors and cofactors. This protein also acts as a metastasis suppressor. Several alternatively spliced transcript variants encoding different isoforms have been described for this gene. |
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Applications: |
ELISA, IHC |
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Name of antibody: |
MED23 |
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Immunogen: |
Synthetic peptide of human MED23 |
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Full name: |
mediator complex subunit 23 |
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Synonyms: |
SUR2; CRSP3; MRT18; SUR-2; ARC130; CRSP130; CRSP133; DRIP130 |
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SwissProt: |
Q9ULK4 |
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ELISA Recommended dilution: |
5000-10000 |
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IHC positive control: |
Human ovarian cancer; |
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IHC Recommend dilution: |
30-150 |

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021-54845833/15800441009
